Join waitlist
Pre-launch · India & Europe

Know your age at the organ level. Track how it changes.

Longevity Clock is developing a blood test that measures 80+ metabolites and turns them into a biological age estimate for six organ systems: liver, kidney, cardiovascular, neuro, mitochondrial and metabolic. It is a wellness tool, built on published cohort research, with calibration for Indian and European populations as a core goal.

Join the waitlist See how it works
  • Planned LC-MS/MS metabolomics panel
  • Grounded in peer-reviewed studies
  • Wellness product, not a diagnostic
  • Beta planned for 2027
Illustrative sample, not real data
Organ Longevity Index (OLI) −4 yrs
31
Biological age
Chronological
35 years
Cardiovascular28 yrs
Metabolic29 yrs
Neuro33 yrs
Kidney30 yrs
Mitochondrial38 yrs
Liver27 yrs
Example report layoutGet early access →
80+
Target metabolites
6
Organ modules
7
Key studies we build on
75
Founding beta places
2027
Target launch
The problem

Standard blood tests miss the silent aging

Organs don't age in lockstep. In a study of 5,676 adults, nearly 1 in 5 people showed strongly accelerated aging in at least one organ.

Oh et al., Nature 2023 · doi:10.1038/s41586-023-06802-1

Routine clinical panels are designed to detect disease once values move outside a reference range. They say little about how fast each organ system is aging. Circulating metabolites reflect energy metabolism, detoxification, inflammation and mitochondrial function, which makes them a natural readout for organ-level aging.

44,168 people
14 circulating biomarkers predicted 5- and 10-year mortality better than conventional risk factors (C-statistic 0.84 vs 0.77). Deelen et al., Nat Commun 2019
118,461 people
Plasma metabolic biomarkers in UK Biobank associate with incidence and mortality of over 700 diseases. Julkunen et al., Nat Commun 2023
The India gap
Most large metabolomics reference cohorts are European. Calibrating organ-level scores for Indian populations is a central part of our beta programme.
Measurable change
Metabolite profiles respond to diet, activity and body weight, so repeat testing can show whether scores move over time.
Why we're building this

A question that no test could answer

I'm a PhD researcher in molecular oncology at IFOM in Milan, where I work on genome stability and how cells respond to DNA damage, two of the core processes behind both aging and cancer.

Large European biobanks have already shown that blood metabolite signatures track disease and mortality risk. That knowledge hasn't been turned into something a person in India or Europe can use to see which organ systems need attention before disease appears.

Longevity Clock is being built to close that gap: a serum metabolomics panel, calibrated for Indian and European populations, delivered as a wellness tool with a repeat-testing loop.

PhDMolecular oncology · IFOM Milan
2 marketsIndia and Europe
Evidence-firstEvery claim linked to a study
Development roadmap
✓
2024–2025 · Completed
Science foundation
Literature review of 80+ candidate metabolite biomarkers · OLI module architecture designed · Domain portfolio secured · Concept manuscript drafted
▶
2026 · In progress
Company setup and lab partnerships
Company formation · Search for an accredited LC-MS/MS lab partner · Pilot panel design · Waitlist recruitment
H2
H2 2027 · Target
Launch in India and Europe
Public OLI test · App MVP · Corporate wellness pilots · EU and India regulatory review
How it will work

From a blood draw to an organ-level report

Five steps from sample to report. Details may change as we validate the panel.

1

Sample collection

A small serum sample, collected at a partner centre or with a home kit. Preparation instructions confirmed before launch.

2

LC-MS/MS analysis

80+ metabolites quantified by liquid chromatography–mass spectrometry at an accredited partner lab.

3

OLI scoring

Machine-learning models (penalised regression and gradient boosting) estimate an age for each organ module.

4

Your report

Per-organ scores, the metabolites behind them, and where you sit against the reference cohort.

5

Re-test and track

Repeat every 6–12 months to see how each organ score moves with lifestyle changes.

OLIOrgan Longevity IndexSix organ modules from one serum metabolomics panel

Your body doesn't age as one number

One person's cardiovascular markers can look young while their kidney markers look older. OLI is designed to show that map, so you know where to focus.

1

Measure 80+ metabolites

Bile acids, uremic toxins, ceramides, NAD⁺ intermediates, branched-chain amino acids, acylcarnitines and more.

2

Map to 6 organ modules

Each metabolite group is assigned to its main organ-system pathway, with weights learned from reference data.

3

Compare with reference cohorts

Initial references come from published European studies. Indian calibration will be built during the beta.

4

Combine into one reading

A composite model brings the six module scores together into an overall Longevity Clock age.

European reference · published cohorts
India calibration · in development
Beta · 75 participants planned

Liver

Primary and conjugated bile acids · hepatic lipid metabolites · amino acid detoxification markers

Kidney

Uremic toxins (indoxyl sulfate, p-cresyl sulfate) · creatinine pathway · organic anion transport

Cardiovascular

Ceramides · lysophosphatidylcholines · TMAO · plasmalogens · oxidised lipid species

Neuro

Tryptophan–kynurenine axis · sphingolipids · serotonin precursors · neuroinflammation markers

Mitochondrial

NAD⁺ intermediates (NMN, NAM) · acylcarnitines · TCA cycle intermediates

Metabolic

Branched-chain amino acids · citrate · α-ketoglutarate · insulin resistance markers

Peer-reviewed science

Built on published research

The studies that shape OLI's design, with the reason each one matters.

✓ Every link verified against PubMed · Oct 2026
Nature Communications2019

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

Deelen J et al.

14 blood biomarkers predicted mortality better than conventional risk factors.

MetabolomicsNMRMortality
PubMed ↗DOI ↗PMID 31431621
Nature2023

Organ aging signatures in the plasma proteome track health and disease

Oh HS-H et al. (Wyss-Coray lab, Stanford)

Showed organs age at different rates within a person, using blood proteins. OLI applies the same idea to metabolites.

Organ agingProteomics
PubMed ↗DOI ↗PMID 38057571
Circulation2015

Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts

Würtz P et al.

Linked specific circulating metabolites to future cardiovascular events, informing the cardiovascular module.

MetabolomicsNMRCVD risk
PubMed ↗DOI ↗PMID 25573147
Nature Medicine2020

Personal aging markers and ageotypes revealed by deep longitudinal profiling

Ahadi S et al. (Snyder lab, Stanford)

Found that individuals follow different aging patterns ("ageotypes") across organ-related pathways.

AgingAgeotypesMulti-omics
PubMed ↗DOI ↗PMID 31932806
Nature Communications2023

Atlas of plasma NMR biomarkers for health and disease in 118,461 individuals from the UK Biobank

Julkunen H et al.

Mapped blood metabolic biomarkers to over 700 diseases, a reference for module design.

MetabolomicsUK Biobank
PubMed ↗DOI ↗PMID 36737450
Nature Communications2016

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

Kettunen J et al.

Showed how strongly genetics shapes circulating metabolite levels, relevant to calibrating across populations.

NMRMetabolomics
PubMed ↗DOI ↗PMID 27005778
Aging Cell2021

Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans

Sebastiani P et al. (New England Centenarian Study)

Circulating signatures of exceptional longevity, useful for defining what healthy aging looks like.

AgingProteomicsSurvival
PubMed ↗DOI ↗PMID 33512769

These are independent studies. None of them evaluated Longevity Clock or the OLI test.

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The Longevity Science Brief

Weekly summaries of new aging and longevity papers, from molecular pathways to what they mean in practice. Written by a working researcher.

MolecularMetabolomics · epigenetics · proteomics
SystemsOrgan aging · cohorts · trials
PracticalWhat it means for interventions

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How we compare

Where OLI fits

How the planned OLI test compares with the main types of aging test on the market.

FeatureLongevity ClockBlood-panel appsGlycan testsEpigenetic clocksMicrobiome tests
Organ-level biological age✓ 6 systems Planned~ Categories✗~ Some products✗
What is measured80+ serum metabolites (LC-MS/MS)Routine clinical markersIgG glycansDNA methylationGut microbial RNA/DNA
India-specific calibration~ In development✗✗✗✗
Reference dataPublished European cohorts + betaProprietaryPublished cohortsPublished cohortsInternal
Lifestyle tracking app✓ Planned✓✗~✓
MarketsIndia + EU/UK PlannedMostly USEU/UKUS/UKVaries
Regulatory categoryWellness (not diagnostic)WellnessWellnessWellnessWellness

Categories summarise typical products from public information, October 2026. Longevity Clock is in pre-launch development.

DashboardConcept mockup
34

Biological age · −3.5 yrs vs. first test

Cardiovascular
28y
Neuro
34y
Mitochondrial
38y
Metabolic
30y
Kidney
31y
Liver
27y
The app

See how your scores move over time

After your test, the planned Longevity Clock app tracks the habits that matter for each organ module and shows progress between tests.

Organ-level trends

Follow each of the six organ scores across tests, alongside sleep, diet, activity and stress.

Focused action plan

Evidence-based lifestyle suggestions aimed at your lowest-scoring module.

Weekly nudges

Short, practical prompts tied to the pathways your results point to.

Re-test and compare

A side-by-side comparison of each test, so you can see what changed.

Plans

Plans for every stage

Pricing will be set by region and confirmed before launch. Register interest and we'll send a quote.

OLI test
Single test
One-time

One metabolomics panel with a full organ-level report.

  • 80+ metabolites by LC-MS/MS
  • 6-module OLI report
  • PDF and online dashboard
  • Accredited partner lab
  • 3 months of app access
Annual membership
Annual plan
2 tests per year

Two tests six months apart, plus the full app.

  • 2 OLI tests, 6 months apart
  • Full Longevity Clock app
  • Personal action plan
  • Organ-level trend dashboard
  • Weekly nudges
  • Year-on-year comparison report
Premium+ membership
Premium plan
4 tests per year

Quarterly testing with clinician review and coaching.

  • 4 OLI tests, quarterly
  • Clinician-reviewed report via partners
  • Personalised nutrition plan
  • Quarterly 30-minute coaching call
  • Everything in Annual
  • Optional research cohort participation

Corporate wellness

Volume pricing for employee health, executive health and insurance-linked wellness programmes.

Team

The people behind the clock

An early-stage team building organ-level metabolomics aging tests for India and Europe.

RC

Ramveer Choudhary

Founder

PhD researcher in molecular oncology at IFOM, Milan. Works on genome stability, the DNA damage response and cancer genomics. Background in pharmacy and computational biology.

LinkedIn ↗
CSO

Open role

Chief Science Officer

Metabolomics or clinical biochemistry background, to lead assay development and validation.

Get in touch →
CFO

Open role

Chief Financial Officer

Healthtech or startup finance experience, to lead fundraising and expansion across India and Europe.

Get in touch →
Research committee · forming

Scientific oversight

An independent committee to review OLI scoring methods, cohort validation and biomarker selection.

Ethics and data governance

Oversight of participant data protection, GDPR and India's DPDP Act 2023, and research ethics.

Metabolomics leadOpen seat
Aging biology expertOpen seat
Biostatistics and cohort methodsOpen seat
Advisory board · forming
Clinical advisorPreventive and precision medicine
Commercial advisorHealthtech and diagnostics
Europe market advisorEU regulation and wellness
Investor advisorLongevity and biotech

Join our scientific network

We're looking for advisors, committee members and research collaborators in metabolomics, aging biology and precision medicine, in India and Europe.

Partner with us
Contact

Let's talk about longevity

Interested in the OLI test, a corporate partnership, investment, or joining the research network? Send a message or write to us directly.

General enquirieshello@longevityclock.eu
Investors and partnershipsinvestors@longevityclock.eu
Research collaborationscience@longevityclock.eu
Based inMilan, Italy · building for India and Europe

Send us a message

Your details are used only to reply to you, in line with GDPR and India's DPDP Act 2023.

Beta programme · 2027

Apply for our founding cohort

We're recruiting 75 people across India and Europe for the OLI beta in 2027. Beta participants help validate the scoring models, receive their report at cost price, and help shape the product.

50 placesIndia · Bangalore, Delhi, Mumbai
25 placesEurope · Italy, Estonia, Netherlands, UK

No spam. We'll only contact you about the beta and launch.

Important notice

Longevity Clock is a wellness product in development, not a medical device or diagnostic test. OLI scores are intended to give research-informed estimates of metabolic wellness indicators. They are not intended to diagnose, treat, cure or prevent any disease.

Sample reports on this site are illustrative only and are not real results. Features, pricing and availability may change. The product is not currently available to buy.

Studies cited on this site are independent published research and did not evaluate Longevity Clock. Always consult a qualified healthcare professional before making health decisions.